Plasma Derived Medicinal Products PDMPs are essential Medicines derived from human plasma.

Diseases and disorders treated with Plasma Derived Medicinal Products:


  • Burns
  • Liver failure
  • Lung injury
  • Major surgery
  • Sepsis
  • Shock
  • Trauma

Alpha-I Proteinase Inhibitor Concentrate

  • Alpha-1 antitrypsin deficiency

Clotting Factor Concentrates

  • Antithrombin Ill deficiency
  • Factor VII deficiency
  • Fibrinogen deficiency
  • Haptoglobin deficiency
  • Hemophilia A
  • Hemophilia B
  • Thrombin deficiency
  • Von Willebrand disease

Polyvalent Immune Globulin

  • Primary Immunodeficiency diseases
  • Secondary Immunodeficiency diseases
  • Bone marrow transplant
  • B-cell chronic lymphocytic leukemia
  • Pediatric HIV
  • Guillain BarrĂ© Syndrome
  • Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
  • Idiopathic Thrombocytopenic Purpura (ITP)
  • Kawasaki disease
  • Other auto-immune and inflammatory diseases

Hyper Immune Globulins

  • Cytomegalovirus
  • Hepatitis A
  • Hepatitis B
  • Respiratory Syncytial Virus (RSV)
  • Rabies
  • Anti-D to prevent Haemolytic Disease of the Newborn
  • Tetanus
  • Vaccinia
  • Varicella Zoster

For further information please click here to access the article “Evidence-based clinical indications of plasma products and future prospects”, published 21 December 2017 in Annals of Blood.


Patients’ Safety

Patient safety underpins all activities of IPFA and its member organisations. Safety factors include product safety, access, security and affordability of supply and appropriate regulation.